If you're trying to keep up with the rapid progress in synthetic biology or genomics generally, here's a nice get-you-up-to-speed primer (PDF) from Scott Mohr. Dating from mid-2007, it only contains one of three sections advertised in the front matter, that on 'Molecular Biology for Novices', but that's 73 pages of reasonably dense material right there.
I grew up on "Blue Book Biology" a 'few years' ago, and amazingly it's still in print, in its ninth edition. That plus the intervening years of perusing the odd Scientific American (more recently, American Scientist) article left me able to follow things like the Church and Venter talk, but lacking confidence that I had the whole story. Mohr's piece is a good level set for those with similar aging or informal backgrounds. What's interesting is that the understanding of what is going on in the cell hasn't changed that much from my high school BSCS days, but the understanding of how it happens has grown immensely more sophisticated and - increasingly - modifiable.